Vitamin D and Omega-3 Slow Aging

Previously in DO-HEALTH (including all 2,157 participants), we reported that omega-3 alone reduced the rate of infections by 13% (ref. 22) and the rate of falls by 10% (ref. 23), and all three interventions combined showed a significant additive benefit on reducing prefrailty by 39% (ref. 24) and incident invasive cancer by 61% (ref. 25) over a 3-year follow-up. The aim of the DNAm analysis in DO-HEALTH Bio-Age was to assess the effects of the interventions at the molecular level. Three of th...

 Exercise Prevents Spending Calories on Fat Storage and Ot...

The reason for that is because exercise causes stress and that stress turns on a whole raft of beneficial effects. And there are really two kinds of this stress. Now, the first kind is energetic stress. Like I went for a run this morning, I spent probably about 500 calories running and I can only do so many things with the calories my body has. And if I spend 500 extra calories exercising, that means I'm not gonna spend 500 calories on other activities that my bother body might engage in. An...

 Exercise Creates Structural Stress

Now, the other kind of stress Structural stress from activity that physical activity cause is structural stress. Now, when I was running this morning, for example, my mitochondria were generating all kinds of ATP to fuel my body, but my mitochondria were also spewing out all kinds of reactive oxygen species, which cause widespread damage throughout my body. I was getting mutations in my DNA, those that damage is causing my telomeres at the end of my chromosomes to shorten its damaging cells. ...

 Why Humans Evolved to be Active

Humans of all to be much more physically active than our ape ancestors. Typical chimpanzee walks maybe two to three kilometers a day, and they take maybe what, three, 4,000 steps a day. A typical hunter-gatherer takes about 15 to 20,000 steps a day. Per kilo hunter-gatherers spend about twice as much energy per kilo on being physically active per day than our ape cousins. And importantly, that physical activity occurs as we age, right? So Americans are pretty inactive, as we all know. A typ...

 Diaphragm Exercises Reduce Blood Pressure

"The muscles we use to breathe atrophy, just like the rest of our muscles tend to do as we get older," explains researcher Daniel Craighead, an integrative physiologist at the University of Colorado Boulder. To test what happens when these muscles are given a good workout, he and his colleagues recruited healthy volunteers ages 18 to 82 to try a daily five-minute technique using a resistance-breathing training device called PowerBreathe. The hand-held machine — one of several on the market ...

 Esports Workout Regimen

Eating right, sleeping right, exercising, cleaning up for sponsors — these ideas have undergirded traditional sports for generations. In e-sports, they are regarded as almost radical. “They don’t look at themselves as physical human beings,” said Hvidt, who won the European handball championship with Denmark in 2008. “It’s common sense, in a way. But with them it was not.” Rfrsh has a validating narrative under its belt. The company’s other team, Astralis, which competes in...

 Exercise Meaningful in Having Good Mental Health

In this cross-sectional study, we analysed data from 1 237 194 people aged 18 years or older in the USA from the 2011, 2013, and 2015 Centers for Disease Control and Prevention Behavioral Risk Factors Surveillance System survey. We compared the number of days of bad self-reported mental health between individuals who exercised and those who did not, using an exact non-parametric matching procedure to balance the two groups in terms of age, race, gender, marital status, income, education l...

 Physiological Decline in the Body When You Stop Exercising

...regular endurance exercise leads to four major consequences: Increased ability of the heart to eject blood increased ability of the blood vessels to send blood to where blood is needed Increased number of capillaries (the vessels that deliver oxygen and ‘food’ to the muscles) increased size and the number of mitochondria (the “power plants” of the cells). All these changes lead to the more efficient use of oxygen, as well as nutrients. [...] Pino considers a person who can run...